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However, the histological picture of basalioma is as diverse as its clinical forms. Therefore, its clinical and cytological differential diagnosis with other skin diseases plays an important role. Flat superficial basalioma is differentiated from lupus erythematosus, lichen planus, seborrheic keratosis, and Bowen's disease. Sclerodermiform basalioma is differentiated from scleroderma andsoriasis, pigmented form - from melanoma. If necessary, additional laboratory tests are carried out to exclude diseases similar to basalioma.
The main complications of basalioma are related to the fact that it can spread to surrounding tissues, causing their destruction. Severe complications, even death, occur when the process affects the bones, ears, eyes, brain membranes, etc. Diagnosis is carried out by cytological and histological examination of a scraping or smear-imprint taken from the surface of the tumor. During the study under a microscope, strands or nest-like clusters of cells of a round, spindle-shaped or oval shape are found. On the edge of the cell is surrounded by a thin rim of the cytoplasm.
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The method of treatment of basalioma is selected individually depending on the size of the tumor, its location, clinical form and morphological appearance, the degree of germination in neighboring tissues. Primary is the occurrence of a tumor or recurrence. The results of previous treatment, age and concomitant diseases of famotidine pills are taken into account. Surgical removal of a basalioma is the most effective and most common way to treat it. The operation is performed with limited tumors located in relatively safe places for surgical intervention. The resistance of the basalioma to radiation therapy or its recurrence is also an indication for surgical removal. In case of sclerodermiform basalioma or tumor recurrence, excision is performed using a surgical microscope.
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Cryodestruction of a basalioma with liquid nitrogen is a quick and painless procedure, but it is effective only in cases of superficial location of the tumor and does not exclude the occurrence of recurrence.
Radiation therapy of basalioma with a small size of the I-II stage process is carried out by close-focus pepcid therapy of the affected area. In the case of an extensive lesion, the latter is combined with remote gamma therapy. In difficult cases (frequent relapses, large tumor size or deep germination), radiotherapy can be combined with surgical treatment. Laser removal of basal cell carcinoma is well suited for older people in whom surgical treatment can cause complications.
It is also used in the case of localization of basalioma on the face, as it gives a good cosmetic effect.
Local chemotherapy of basalioma is carried out by applying applications of cytostatics (fluorouracil, metatrexate, etc.) to the affected areas of the skin.
In general, due to the absence of metastasis, the prognosis of the disease is favorable. But in advanced stages and in the absence of adequate treatment, the prognosis of basalioma can be very serious. Early treatment of basalioma is of great importance for recovery. Due to the tendency of basalioma to recur frequently, a tumor larger than 20 mm is already considered advanced. If the treatment is carried out until the tumor has reached such a size and has not begun to grow into the subcutaneous tissue, then in 95-98% there is a stable cure. When the basalioma spreads to the underlying tissues, significant cosmetic defects remain after treatment.
Causes, symptoms, signs, diagnosis and treatment of pathology.
Basalioma is a malignant tumor that grows from the deepest basal layer of the epidermis. It is the most common type of skin cancer in most parts of the world, accounting for approximately three-quarters of famotidine pills tumors. Males are predominantly affected. Basalioma can develop at any age, but about a third of reported cases are in patients over 40 years of age. An increase in the frequency of basaliomas is observed in countries with a hot climate and a high average annual rate of ultraviolet radiation.
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It is characterized by slow growth and lack of metastasis. The most common localization of these tumors are exposed parts of the body, however, these tumors are predominantly located on the chest, neck and head. Due to the slow imperceptible growth, this neoplasm can go unnoticed by both the patient and the doctor for a long time and can be detected only in advanced stages. Despite the fact that this tumor does not metastasize, it can lead to serious consequences. Its localization in the region of the eye sockets, nose, mouth and auricles is especially dangerous, since during germination it significantly deforms the cartilaginous and even bone basis of these organs and leads to a pronounced violation of their function. In addition, the natural openings of these organs provide a pathway through which basaliomas can enter the skull and even affect the brain. Thus, this tumor, which has a non-aggressive behavior in comparison with other malignant tumors, under certain circumstances can even lead to death.
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Diagnosis and treatment, as a rule, does not cause difficulties. Most forms of this cancer respond successfully to both radiation and surgical treatment. Medical treatment is also applicable, but due to the predominantly local nature of this tumor, it is rarely used. The likelihood of tumor recurrence depends on its size, penetration depth and the chosen method of treatment, but there are other factors that can affect this process. Given the slow growth, lack of hematogenous metastasis, and high cure rates, the prognosis for this disease is generally considered to be favorable. Causes of basalioma.